Thursday, March 30, 2017

Book Review and Thoughts: Secret Life of Fat

The Secret Life of Fat is a book by Sylvia Tara.  Reading this book gave me a new understanding of this organ, yes organ, just like your liver.  It is much more then the blubber we think of when we pinch that inch.  It also gave me more empathy of the plight of someone that is "constantly" trying to lose weight.  Essentially, the body is rigged to prevent you from winning, and when you do think you won and let your guard down, it strikes again.  Fat is smart.  It can think.  Think about that for a bit.  I took copious amount of notes but I'll go through and highlight some important ones with recommendations on lifestyle to try to keep fat working for you instead of becoming a health risk. 

There are three types of fat.  White fat, brown fat, and beige fat.  White fat is what we usually think of, the stuff we are always trying to get rid of.  Brown fat is fairly new discovery in the last 10 or so years.  Brown fat actually raises metabolism and burns white fat.  Beige fat can become white or brown.  This will be influence by our environment and stressors.  Think exercise.

Here is an example of the FAT LOOP that we see all to often.  
1.  We eat to much
2.  Fat cells grow until they are overcrowded
3.  Send out signals to immune cells to send macrophages to engulf the fat cells. 
4.  Inflammation/chronic
5.  Fat no longer responds well to insulin
6.  Pancreas has to produce more insulin
7.  The loop of constantly needing more insulin as cells become more insulin resistant.
8.  Cells are not getting the sugar and fats from our blood and are starved for nutrients.
9.  This makes us hungrier.
10.  We eat more.  The loop starts again.


There are different types of white fat.  Subcutaneous (close to the surface)  Think of jiggly fat.  Visceral fat.  Deep and close to the organs.  Ever pat a beer belly and it's hard, that is visceral fat and that is dangerous.  It emits more hormones and cytokines (inflammations) and is correlated with diabetes, heart disease and even dementia.

The hormones to know. Adiponectin, this sensitizes the bodies response to insulin.  Guides sugar/fat out of our bloodstream and into subcutaneous fat.  It removes toxic lipids called ceramides.  We can increase adiponectin with vigorous exercise.  Leptin is a hormone that makes us feel full, it inhibits hunger.  Ghrelin is it's opposite, Ghrelin will make you feel hungry.  Lack of sleep produces a bad combo of low Leptin and high Ghrelin.  

How Your Set Up To Lose
You have lost fat, it's now harder to keep it off then someone that has never gained weight.  Losing weight makes you more responsive to food and less able to control intake.  It appears this doesn't go away.  The hormone levels appear to alter bodies that have lost weight to be hungrier then before they had lost weight.  Not only that, but the metabolism was lowered at the reduced fat.  You can see why it's called "yo-yo dieting."  What you ate to lose weight, will eventually become enough to make you gain that weight back.

The danger of this cycle is that often the subcutaneous fat that is lost comes back as visceral fat.  In liposuction, most ended up regaining the same percentage of fat, but in different areas with more visceral fat and with less healthy fat.  The one way this was stopped is when after liposuction the individual took up exercise.

Onto some of the craziness.  Virus can potentially be causing obesity.  The virus AD-36 has been shown to crossover from chicken to chicken.  Studies have confirmed this.  From an ethics stand point you can't really reproduce this in people.  One lead researcher in this believes 30% of all obese individuals have this virus in them.  (He states there is no cure at the moment, but what you eat and how you exercise is still up to you, you just may have to work harder)

Your gut biome is insanely important with fat gain.  Lean individuals have a more diverse gut bacteria.  In fact, as you lose fat you lose bacteria called Firmicutes and gain Bacteroidetes.   The gut bacteria influence the fat storage in a few ways.  The microbes have enzymes we don't carry and can thus digest parts of the plants that our own digestive system can't.  Ultimately, the bacteria change digestion in two ways, improving the ability of the gut to absorb food and increasing the amount of sugar extracted.  

When fat mice were given the gut flora of lean mice, they got lean.  When lean mice were given the fat mice gut flora they got fat. 

Genes influence our resting metabolism, fat percentage, abdominal visceral fat, triglycerides and cholesterol.  So it's not just lazy or lack of effort for weight gain.  This can take some stress away, but it doesn't mean losing fat can't be done and shouldn't be a goal.  Because, the trump card, is vigorous exercise.  It has shown to erase genetic variables.  If you are an individual that genes are against, it means you may not get a cheat day or cheat meal.  You will have to be more diligent.  We all know that guy that eats McDonalds and has a 6 pack without doing much.  The opposite is also true.  Accept it and move on.  

Women tend to store more fat then men in every culture across the world.  They also tend to have what is called a better compensating pattern after exercise then men.  This means that men in general underestimate what was burned and eat less to return to caloric neutral.  Women tend to do this better so they estimate what to eat more close to what they burned.  They think this is a biological pattern to ensure health.  

Fat cells have receptors for hormones.  As we age, we are producing less hormones that tell us to burn fat, so we tend to gain fat.  At the same time we produce more hormones such as cortisol. Cortisol is a hormone correlated with abdominal fat.  Can you see another cycle?  

The old saying in rehab is that the most likely injury is the one you already have had.  It's kind of a weak way of saying don't get hurt.  In fat loss, the best way is to not allow yourself to gain that extra 15 pounds, because there are metabolic consequences that come from this.  Now onto real advice.

1.  Shift the mindset from, I'll lose this 20 pounds and resume normal life, to I'm going to change my lifestyle and lose weight in the process.  The yo-yo weight gain will happen if you don't.  I've already told you this can lead to more dangerous fat levels.  In fact, I wouldn't start the process without this commitment.  

2.  Improve sleep.  Get this capstone in place.  You are fighting an uphill battle as it is, why push the stone up the hill in the process.  

3.  Weight loss has to come through nutrition.  Don't add exercise into the equation until you got the nutrition dialed in.  You should be able to lose weight without exercise.  Don't move to exercise until the nutrition is in place.  

4.  Nutrition should be focused on the gut biome.  Changes there will have bigger implications.  Soluble fibre is big.  Get 6-8 fist sized vegetables every day. 

5.  Vigorous exercise is now added.  30min 5x a week is a minimum.  In the book, this was defined by 4-6mph of running.  Biking at 12-14 miles per hour.  Lifting weights.  If you ran 20 miles a week at age 30, it will most likely take about 30 miles a week at age 40 to maintain that same metabolism.  

Genetics plays a huge role.  In the end, you are still in control of the process.  The process may be harder or easier, but it's still our each individual choice

1 comment:

assignment writing help said...

i have used so many things to try and lose fat but all in vain. i will try to look into this and see if anything can be of help to me. Thanks for posting.